About Wegovy Tablets
Wegovy tablets are a prescription-only medicine designed to support weight loss and long-term weight management in adults living with obesity or overweight with weight-related health conditions. They contain semaglutide, a GLP-1 receptor agonist that works by helping regulate appetite, increasing feelings of fullness and reducing hunger, making it easier to maintain a calorie-controlled diet.
Taken once daily as prescribed, Wegovy tablets provide a convenient oral treatment option for suitable patients. For the best results, treatment should be combined with a healthy diet, regular physical activity and ongoing lifestyle changes.
Why Choose Wegovy Tablets?
Wegovy tablets may offer several benefits for people looking for a convenient weight management treatment.
• Effective Weight Loss: Clinical studies have shown that semaglutide can help patients achieve significant weight loss when combined with healthy lifestyle changes.
• Convenient Daily Tablet: An oral treatment option for those who prefer not to use injectable medication.
• Gradual Dose Escalation: Treatment begins at a lower dose and is increased gradually to help improve tolerability and reduce gastrointestinal side effects.
• Improved Health Outcomes: Weight loss may help improve blood pressure, cholesterol levels, blood sugar control and overall health in appropriate patients.
This medication may be suitable for adults with a BMI of 30 kg/m² or above, or 27 kg/m² or above with at least one weight-related medical condition, following assessment by one of our clinicians. Wegovy tablets should only be used under the supervision of a qualified healthcare professional and are not intended to be used alongside other prescription weight loss medicines unless specifically advised.
Important Information
Wegovy tablets are prescription-only and require approval following a clinical assessment. It is important to take the medication exactly as prescribed and attend any recommended follow-up reviews. Regular monitoring of your progress helps ensure treatment remains safe, appropriate and effective.
Directions
How to Take Wegovy Tablets
• Take one Wegovy tablet once daily, exactly as prescribed by your clinician.
• Take the tablet first thing in the morning on an empty stomach.
• Swallow the tablet whole with up to 120 mL (approximately half a glass) of plain water. Do not crush, split or chew the tablet.
• Do not eat, drink (other than plain water) or take any other oral medicines for at least 30 minutes after taking your tablet. This helps ensure the medicine is absorbed properly.
• Try to take your tablet at the same time each day to establish a routine.
• If you miss a dose, skip the missed dose and take your next tablet at the usual time the following day. Do not take two tablets on the same day.
• Follow the prescribed dose escalation schedule as advised by your clinician.
Storage
• Store below 30°C in the original blister pack until ready to use.
• Keep the blister pack dry and protect it from moisture.
• Do not use the tablets after the expiry date shown on the packaging.
• Keep all medicines out of the sight and reach of children.
Important Information
Wegovy tablets are a prescription-only medicine and should only be taken under the supervision of a qualified healthcare professional. Attend your scheduled follow-up reviews so your clinician can monitor your progress, assess any side effects and adjust your treatment if required. For best results, treatment should be combined with a reduced-calorie diet, increased physical activity and long-term healthy lifestyle changes.
Side Effects
Like all medicines, Wegovy tablets can cause side effects, although not everybody experiences them. Most side effects are mild to moderate, occur during the first few weeks of treatment and improve as your body adjusts to the medication.
Common Side Effects
• Nausea
• Diarrhoea
• Vomiting
• Constipation
• Stomach (abdominal) pain
• Indigestion
• Reduced appetite
• Headache
• Fatigue (tiredness)
• Heartburn (acid reflux)
• Bloating or wind
Less Common Side Effects
• Dizziness
• Burping
• Changes in taste
• Dehydration (usually due to vomiting or diarrhoea)
• Increased heart rate
• Injection site reactions (not applicable to the tablet formulation)
• Mild allergic skin reactions
Serious Side Effects (Rare)
Seek urgent medical advice if you experience:
• Pancreatitis – severe, persistent abdominal pain that may spread to your back, with or without vomiting.
• Gallbladder problems – severe pain in the upper right abdomen, fever or jaundice.
• Kidney problems – reduced urine output or signs of dehydration.
• Severe allergic reaction (anaphylaxis) – swelling of the face, lips, tongue or throat, difficulty breathing or severe rash.
• Severe dehydration caused by prolonged vomiting or diarrhoea requiring medical treatment.
• Changes in vision, particularly if you have diabetes.
When to Contact Your Clinician
Contact your clinician if:
• Side effects are severe or persistent.
• You are unable to keep fluids down.
• You develop severe abdominal pain.
• You notice yellowing of the skin or eyes.
• You experience symptoms of an allergic reaction.
Reducing Side Effects
Many side effects can be minimised by:
• Eating smaller meals.
• Avoiding high-fat or spicy foods.
• Drinking plenty of fluids.
• Taking the medication exactly as prescribed.
• Following the recommended dose escalation schedule.
• Contacting your clinician if symptoms do not improve.
Most patients find that side effects lessen over the first few weeks as their body adjusts to treatment. Regular follow-up appointments with our clinicians help ensure your treatment remains safe, effective and well tolerated.
Warnings
Do Not Take Wegovy Tablets If You:
• Are allergic to semaglutide or any of the other ingredients in the tablets.
• Have a personal or family history of medullary thyroid carcinoma (MTC).
• Have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Are pregnant or think you may be pregnant.
• Are breastfeeding.
Speak to Your Clinician Before Taking Wegovy Tablets If You:
• Have a history of pancreatitis.
• Have severe stomach or bowel disorders, including gastroparesis (delayed stomach emptying).
• Have kidney disease or liver impairment.
• Have gallbladder disease or gallstones.
• Have type 2 diabetes and diabetic eye disease (diabetic retinopathy).
• Are taking insulin or medicines such as sulfonylureas, as your treatment may need adjusting.
• Have a history of severe dehydration or recurrent vomiting.
Pregnancy and Fertility
• Wegovy tablets should not be used during pregnancy.
• If you are planning to become pregnant, stop treatment at least two months before trying to conceive.
• Use effective contraception while taking Wegovy tablets if appropriate.
Age Restrictions
• Wegovy tablets are not recommended for anyone under 18 years of age.
• Use in adults aged 75 years and over is limited, and your clinician will assess whether treatment is suitable.
Important Safety Information
• Take Wegovy tablets exactly as prescribed.
• Do not exceed the recommended dose.
• Attend your scheduled follow-up appointments so your progress can be monitored.
• Seek urgent medical attention if you develop severe abdominal pain, signs of an allergic reaction, or symptoms of pancreatitis.
This medicine is prescription-only and should only be taken following assessment and ongoing supervision by a qualified healthcare professional.
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Wegovy® Oral Tablets are a once-daily prescription treatment containing semaglutide to help eligible adults lose weight and maintain weight loss.
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They contain the same active ingredient (semaglutide) but are taken as a tablet instead of a weekly injection.
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They mimic the naturally occurring GLP-1 hormone, helping to reduce appetite, increase feelings of fullness and reduce food cravings
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In clinical studies, patients taking the highest approved dose achieved an average weight loss of approximately 13.6% over 64 weeks when combined with diet and exercise. Individual results vary.
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Take one tablet every morning on an empty stomach with up to 120 ml of plain water. Wait at least 30 minutes before eating, drinking or taking any other medicines.
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No. They are only suitable following a clinical assessment by a UK prescriber to ensure they are safe and appropriate for you.
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Yes. Wegovy® Oral Tablets work best when used alongside a reduced-calorie diet, increased physical activity and long-term healthy lifestyle changes.
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Wegovy® Oral Tablets have received MHRA approval for weight management. NHS availability may vary and depends on local commissioning and eligibility criteria.
